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Drug-like Molecules:

Drug-likeness is a qualitative concept used in drug design for how "drug-like" a substance is with respect to factors like bioavailability. It is estimated from the molecular structure before the substance is even synthesized and tested. A drug-like molecule has properties such as: Solubility in both water and fat, Potency at the target of interest, small molecule (Eighty percent of traded drugs have molecular weights under 450 daltons), Substructures that have known chemical or pharmacological properties etc. Theoretically, a drug-like molecule has a logarithm of partition coefficient (log P) between -0.4 and 5.6, molecular weight 160-480 g/mol, molar refractivity of 40-130, which is related to the volume and molecular weight of the molecule and has 20-70 atoms. ---Wikipedia, The Free Encyclopedia

Active pharmaceutical ingredient (API):

A substance used in a finished pharmaceutical product (FPP), intended to furnish pharmacological activity or to otherwise have direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease, or to have direct effect in restoring, correcting or modifying physiological functions in human beings.